Yes, of course you can!
With the three dots to the right of every user, you can manage that user specifically.
If you want to manage multiple users at once, you use the buttons at the top of the user management-tab.
What does that mean, 'manage' users? You can manually delete users, add / delete user groups, add/delete a store, and also a job position. And you can change their 'role' from 'user' to 'admin' to 'manager' (Mini CMS with only user management).
To delete admins, first change their user role to 'user', and then you'll be able to delete them.
Pay Attention: if you have an integration running that also updates the user's user groups and stores, you won't be able to add/delete user groups and stores that came in via the integration. Every time a user logs in again, those user groups and stores will automatically be matched with how they're setup in your internal system.